If you are a strong Twitter user (like me) and have a Mac or iPhone/iPad etc, then I strongly suggest you get Tweetbot. It’s my Twitter client of choice, and I have never had any problems with it.
I was delighted to find out they are now testing (in alpha only at this stage) a Tweetbot for Mac. Alpha means it’s the first stage of public testing and isn’t 100% stable. There is still a likelihood that there will be bugs, crashes and other things some users may not want. But if you’re happy with this, then download away and help make a great Twitter client for the Mac.